CHEMICAL CONSTITUENTS OF THE ENDOPHYTIC FUNGUS PENICILLIUM SHEARII ISOLATED FROM PYRROSIA LANCEOLATA (L.) FARW.

Tóm tắt

Endophytic fungi are one of the typical endophytic microorganism groups that have been particularly interested in research recently because of their roles in many aspects; the most special thing is the ability to biosynthesize secondary substances with biological activity such as antioxidant, antibacterial, anti-tumor... The endophytic fungal strains were identified as Penicillium shearii CBS 290.48 by morphological microscopic and DNA sequencing based on the modified Sanger method. From the ethyl acetate fraction of the medium extract of P. shearii, four compounds were isolated and identified as ergosterol (1), dehydroxypaxilline (2), chrysophanol (3), and paspaline (4). Their structures were determined by means of spectroscopic methods (MS, 1D, and 2D NMR).