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ESTABLISHMENT OF AN IN-HOUSE STANDARD FOR PRUNELLAE SPICA
DOI:
https://doi.org/10.63240/jmm-nimm.2026.1+2.213Từ khóa:
In-house standard, Prunellae spica, Qualitative and quantitative analysis, HPLC-ĐA, Rosmarinic acidTóm tắt
This study aimed to establish an in-house quality standard for Prunellae spica (PS) based on the Vietnamese Pharmacopoeia V, incorporating enhanced qualitative and quantitative specifications. The evaluated criteria included description, powder, water content, total ash, acid-insoluble ash, identification by chemical reaction and thin-layer chromatography, quantification of rosmarinic acid using high-performance liquid chromatography with diode array detection according to the Chinese Pharmacopoeia (2020), extractives, and foreign matter. Quantitative analysis of eight PS samples revealed that the rosmarinic acid content ranged from 0.172% to 0.860%, calculated with reference to the dried drug. The developed in-house standard was subsequently applied for the quality assessment of PS samples collected from the market.
