Số lượt xem tóm tắt: 50
Số lượt xem pdf: 0
Số lượt xem pdf: 0
Đã Xuất bản
25-04-2025
Chuyên mục
Bài báo
Cách trích dẫn
PHENOLIC CONSTITUENTS FROM THE LEAVES OF CAMELLIA HAKODAE NINH WITH THEIR α-GLUCOSIDASE INHIBITORY ACTIVITY. (2025). Tạp Chí Dược liệu, 30(2), pp. 92 - 97. https://doi.org/10.63240/jmm-nimm.2025.2.109
PHENOLIC CONSTITUENTS FROM THE LEAVES OF CAMELLIA HAKODAE NINH WITH THEIR α-GLUCOSIDASE INHIBITORY ACTIVITY
DOI:
https://doi.org/10.63240/jmm-nimm.2025.2.109Từ khóa:
Camellia hakodae Ninh, Flavonoid glycoside, α-Glucosidase inhibitory activityTóm tắt
Five phenolic compounds, including methyl 4-hydroxybenzoate (1), syringin (2), genkwanin (3), kaemferol-3-O-rhamnoside (4), and yuankanin (5), were isolated from the 70% EtOH extract of W. indica twigs and leaves. Their structures were identified using nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS) datawith compound 2 being reported for the first time from this plant. The compounds were evaluated for their effects on IL-1β and IL-10 cytokine production in LPS-induced RAW 264.7 macrophages and 3 showed considerably inhibitory activity against IL-1β with an IC50 value of 18.8 ± 2.46 µM.
