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09-08-2026
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Cách trích dẫn
ANTIMICROBIAL COMPOUNDS PRODUCED BY THE MARINE ACTINOMYCETE STREPTOMYCES SP. G668. (2026). Tạp Chí Dược liệu, 27(2), pp. 72 - 76. https://doi.org/10.63240/jmm-nimm.2022.2.399
ANTIMICROBIAL COMPOUNDS PRODUCED BY THE MARINE ACTINOMYCETE STREPTOMYCES SP. G668
DOI:
https://doi.org/10.63240/jmm-nimm.2022.2.399Từ khóa:
Marine actinomycetes, Streptomyces, Alkaloid, Indole, CyclodipeptideTóm tắt
From the ethyl acetate extract of the Streptomyces sp. G668 strain, seven compounds were isolated: 9H-pyrido[3,4-b]indole (1), L-tryptophan (2), indole-3-carboxylic acid (3), 3-indolylacetic acid (4), cyclo-(Pro-Ala) (5), uracil (6), thymine (7). Their structures were elucidated by nuclear magnetic resonance spectroscopy (NMR), mass spectroscopy (MS) and comparison with the reference data. Compound 1 exhibited moderate antibacterial activity against Escherichia coli ATCC25922 and compound 5 strongly inhibited Candida albicans ATCC10231.
