Tải xuống

Số lượt xem tóm tắt: 7
Số lượt xem pdf: 2

Đã Xuất bản

03-04-2026

Số

Tạp chí Dược liệu, Tập 31, Số 1+2/2026

Chuyên mục

Bài báo

Cách trích dẫn

INVESTIGATION OF THE VARIATION OF GYMNEMAGENIN CONTENT IN GYMNEMA R.BR UNDER THE INFLUENCE OF CERTAIN STRAINS OF BACTERIA. (2026). Tạp Chí Dược liệu, 31(1+2), pp. 147 - 153. https://doi.org/10.63240/jmm-nimm.2026.1+2.222

INVESTIGATION OF THE VARIATION OF GYMNEMAGENIN CONTENT IN GYMNEMA R.BR UNDER THE INFLUENCE OF CERTAIN STRAINS OF BACTERIA

Các tác giả

    Tong Thi Thanh Vuong 1 # , Tran Thi Minh Thuy 1 , Le Thi Kim Van 2
  • 1 Faculty of Analytical Chemistry and Drug Quality Control, Hanoi University of Pharmacy, Hanoi, Vietnam
  • 2 National Institute of Medicinal Materials (NIMM), Hanoi 11018, Vietnam

DOI:

https://doi.org/10.63240/jmm-nimm.2026.1+2.222

Từ khóa:

Gymnemagenin, Biotransformation, Incubation

Tóm tắt

The capacity of Lactobacillus casei, Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bacillus subtilis to increase the content of gymnemagenin in Gymnema spp. R.Br was investigated on two samples of G. sylvestre and two samples of G. latifolium by incubating these samples for 8 days with each strain of bacteria. The difference in content of gymnemagenin before and after incubation was determined by using a validated HPLC method meeting all requirements of AOAC International on analytical method performance. The four strains of bacteria were found to increase the content of gymnemagenin in the tested samples after incubation, but the change caused by B.subtilis was not statistically significant. No significant strain-to-strain difference in the capacity to improve the content of gymnemagenin was found among the four strains of bacteria.